After the introduction of the scientific method, there was a marked increase in the pace of breakthrough discoveries. Both science and entrepreneurship operate under conditions of extreme uncertainty, so the thinking goes that the adoption of some entrepreneurial method might do for business innovation what the scientific method did for scientific discoveries: dramatically accelerate the pace. This is the core message of the Lean Startup methodology.
The closest equivalent to a scientific experiment in innovation is a cycle around the Build-Measure-Learn validated learning loop.
However, simply running more experiments is not enough. More cycles around the build-measure-learn loop do not automatically lead to new insights. Many experiments simply invalidate a bad idea and leave you stuck.
So how then do you set yourself up for breakthrough? The answer lies in a deeper understanding of how true science is done.